{05/09} · Imaging
All workCKD Detection from Fundus Photographs with RETFound
Can a photograph of the retina flag chronic kidney disease?
We fine tuned RETFound on 1,472 patients imaged with a handheld camera. Grad-CAM, GradCAM++ and Integrated Gradients were compared by three clinical graders, one engineer and an automated script.
- 1,472patients, imaged with a handheld camera
- 0.825mean five fold patient level AUC
- 0.937AUC on a second camera, after colour harmonisation
What the record supports
Claim
The model separates CKD from non CKD at the same hospital.
Evidence
Mean five fold patient level AUC was 0.825, and 0.937 on a second camera at the same hospital after colour harmonisation. Platt scaling cut external calibration error from 0.311 to 0.035.
Limits, stated plainly
AUC fell to 0.489 on two unrelated public datasets, and the paper reports this plainly.